Andrew S. Judd
AbbVie (United States)(US)
Publications by Year
Research Areas
Synthetic Organic Chemistry Methods, Regulation of Appetite and Obesity, Asymmetric Hydrogenation and Catalysis, Receptor Mechanisms and Signaling, Biochemical Analysis and Sensing Techniques
Most-Cited Works
- → Validation of Diacyl Glycerolacyltransferase I as a Novel Target for the Treatment of Obesity and Dyslipidemia Using a Potent and Selective Small Molecule Inhibitor(2008)139 cited
- → Discovery of A-1331852, a First-in-Class, Potent, and Orally-Bioavailable BCL-XL Inhibitor(2020)127 cited
- → Concise Construction of Novel Bridged Bicyclic Lactams by Sequenced Ugi/RCM/Heck Reactions(2007)104 cited
- → Identification of 2-(4-Benzyloxyphenyl)-N- [1-(2-pyrrolidin-1-yl-ethyl)-1H-indazol-6-yl]acetamide, an Orally Efficacious Melanin-Concentrating Hormone Receptor 1 Antagonist for the Treatment of Obesity(2005)88 cited
- → Slam is an outer membrane protein that is required for the surface display of lipidated virulence factors in Neisseria(2016)75 cited
- → Structural basis for the recruitment of glycogen synthase by glycogenin(2014)55 cited
- → Selective MCL-1 inhibitor ABBV-467 is efficacious in tumor models but is associated with cardiac troponin increases in patients(2023)55 cited
- → Discovery of ((4R,5S)-5-Amino-4-(2,4,5- trifluorophenyl)cyclohex-1-enyl)-(3- (trifluoromethyl)-5,6-dihydro- [1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)methanone (ABT-341), a Highly Potent, Selective, Orally Efficacious, and Safe Dipeptidyl Peptidase IV Inhibitor for the Treatment of Type 2 Diabetes(2006)52 cited
- → Optimization of Chromone-2-carboxamide Melanin Concentrating Hormone Receptor 1 Antagonists: Assessment of Potency, Efficacy, and Cardiovascular Safety(2006)48 cited
- → Discovery and Characterization of Aminopiperidinecoumarin Melanin Concentrating Hormone Receptor 1 Antagonists(2005)48 cited