Kyle V. Butler
Pediatrics and Genetics(US)Icahn School of Medicine at Mount Sinai(US)
Publications by Year
Research Areas
Protein Degradation and Inhibitors, Histone Deacetylase Inhibitors Research, Epigenetics and DNA Methylation, Peptidase Inhibition and Analysis, RNA and protein synthesis mechanisms
Most-Cited Works
- → Rational Design and Simple Chemistry Yield a Superior, Neuroprotective HDAC6 Inhibitor, Tubastatin A(2010)760 cited
- → A Potent, Selective, and Cell-Active Inhibitor of Human Type I Protein Arginine Methyltransferases(2015)283 cited
- → Histone Deacetylase 6 and Heat Shock Protein 90 Control the Functions of Foxp3 + T-Regulatory Cells(2011)250 cited
- → Structure-inspired design of β-arrestin-biased ligands for aminergic GPCRs(2017)175 cited
- → Discovery of a Selective, Substrate-Competitive Inhibitor of the Lysine Methyltransferase SETD8(2014)115 cited
- → Chemical Origins of Isoform Selectivity in Histone Deacetylase Inhibitors(2008)111 cited
- → Second-Generation Histone Deacetylase 6 Inhibitors Enhance the Immunosuppressive Effects of Foxp3+ T-Regulatory Cells(2011)102 cited
- → Novel Inhibitors of Human Histone Deacetylase (HDAC) Identified by QSAR Modeling of Known Inhibitors, Virtual Screening, and Experimental Validation(2009)100 cited
- → Dose-dependent activation of gene expression is achieved using CRISPR and small molecules that recruit endogenous chromatin machinery(2019)83 cited
- → Discovery of G Protein-Biased D2 Dopamine Receptor Partial Agonists(2016)52 cited