Patrick Y. S. Lam
Publications by Year
Research Areas
Blood Coagulation and Thrombosis Mechanisms, HIV/AIDS drug development and treatment, Catalytic Cross-Coupling Reactions, HIV Research and Treatment, Catalytic C–H Functionalization Methods
Most-Cited Works
- → New aryl/heteroaryl CN bond cross-coupling reactions via arylboronic acid/cupric acetate arylation(1998)1,043 cited
- → Rational Design of Potent, Bioavailable, Nonpeptide Cyclic Ureas as HIV Protease Inhibitors(1994)835 cited
- → Copper-Promoted Carbon-Heteroatom Bond Cross-Coupling with Boronic Acids and Derivatives(2010)550 cited
- → Discovery of 1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro- 1H-pyrazolo[3,4-c]pyridine-3-carboxamide (Apixaban, BMS-562247), a Highly Potent, Selective, Efficacious, and Orally Bioavailable Inhibitor of Blood Coagulation Factor Xa(2007)391 cited
- → Pax3 modulates expression of the c-Met receptor during limb muscle development.(1996)360 cited
- → Copper-catalyzed general CN and CO bond cross-coupling with arylboronic acid(2001)318 cited
- → Apixaban, an oral, direct and highly selective factor Xa inhibitor: in vitro, antithrombotic and antihemostatic studies(2008)299 cited
- → Copper-Promoted C−N Bond Cross-Coupling with Hypervalent Aryl Siloxanes and Room-Temperature N-Arylation with Aryl Iodide(2000)235 cited
- → Flexibility and function in HIV-1 protease(1995)230 cited
- → Discovery of 1-(3‘-Aminobenzisoxazol-5‘-yl)-3-trifluoromethyl-N-[2-fluoro-4- [(2‘-dimethylaminomethyl)imidazol-1-yl]phenyl]-1H-pyrazole-5-carboxyamide Hydrochloride (Razaxaban), a Highly Potent, Selective, and Orally Bioavailable Factor Xa Inhibitor(2004)188 cited