Kelly Hamilton

Publications by Year

Research Areas

Microtubule and mitosis dynamics, Protein Kinase Regulation and GTPase Signaling, Cancer-related Molecular Pathways, Enzyme Structure and Function, Protein Structure and Dynamics

Most-Cited Works

• → Inhibition of farnesyltransferase induces regression of mammary and salivary carcinomas in ras transgenic mice(1995)538 cited
• → A Farnesyltransferase Inhibitor Induces Tumor Regression in Transgenic Mice Harboring Multiple Oncogenic Mutations by Mediating Alterations in Both Cell Cycle Control and Apoptosis(1998)172 cited
• → Kinesin Spindle Protein (KSP) Inhibitors. 9. Discovery of (2S)-4-(2,5-Difluorophenyl)-N-[(3R,4S)-3-fluoro-1-methylpiperidin-4-yl]-2-(hydroxymethyl)-N-methyl-2-phenyl-2,5-dihydro-1H-pyrrole-1-carboxamide (MK-0731) for the Treatment of Taxane-Refractory Cancer(2008)156 cited
• → Kinesin spindle protein (KSP) inhibitors. Part 1: The discovery of 3,5-diaryl-4,5-dihydropyrazoles as potent and selective inhibitors of the mitotic kinesin KSP(2005)136 cited
• → Digital Reconstructions of Neuronal Morphology: Three Decades of Research Trends(2012)136 cited
• → Resting state EEG correlates of memory consolidation(2016)132 cited
• Preclinical and clinical pharmacodynamic assessment of L-778,123, a dual inhibitor of farnesyl:protein transferase and geranylgeranyl:protein transferase type-I.(2002)
• → 3-Aminopyrrolidinone Farnesyltransferase Inhibitors: Design of Macrocyclic Compounds with Improved Pharmacokinetics and Excellent Cell Potency(2002)84 cited
• → Development of thioquinazolinones, allosteric Chk1 kinase inhibitors(2008)74 cited
• → Kinesin spindle protein (KSP) inhibitors. Part 2: The design, synthesis, and characterization of 2,4-diaryl-2,5-dihydropyrrole inhibitors of the mitotic kinesin KSP(2006)64 cited