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Mark A. Lehrman | doi.page

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Mark A. Lehrman

Southwestern Medical Center(US)The University of Texas Southwestern Medical Center(US)

Publications by Year

Research Areas

Glycosylation and Glycoproteins Research, Carbohydrate Chemistry and Synthesis, Endoplasmic Reticulum Stress and Disease, Lysosomal Storage Disorders Research, Galectins and Cancer Biology

Most-Cited Works

→ Mutation in LDL Receptor: Alu-Alu Recombination Deletes Exons Encoding Transmembrane and Cytoplasmic Domains(1985)463 cited
→ The Molecular Chaperone Calnexin Binds Glc1Man9GlcNAc2 Oligosaccharide as an Initial Step in Recognizing Unfolded Glycoproteins(1995)419 cited
→ Spliced X-Box Binding Protein 1 Couples the Unfolded Protein Response to Hexosamine Biosynthetic Pathway(2014)400 cited
→ The J. D. mutation in familial hypercholesterolemia: Amino acid substitution in cytoplasmic domain impedes internalization of LDL receptors(1986)376 cited
→ Internalization-defective LDL receptors produced by genes with nonsense and frameshift mutations that truncate the cytoplasmic domain(1985)302 cited
→ Duplication of seven exons in LDL receptor gene caused by Alu-Alu recombination in a subject with familial hypercholesterolemia(1987)

289 cited

→ The Lebanese allele at the low density lipoprotein receptor locus. Nonsense mutation produces truncated receptor that is retained in endoplasmic reticulum.(1987)281 cited

→ Oligosaccharide Binding Characteristics of the Molecular Chaperones Calnexin and Calreticulin(1998)256 cited

→ Under normoxia, 2-deoxy-d-glucose elicits cell death in select tumor types not by inhibition of glycolysis but by interfering with N-linked glycosylation(2007)244 cited

→ Alu-Alu recombination deletes splice acceptor sites and produces secreted low density lipoprotein receptor in a subject with familial hypercholesterolemia.(1987)228 cited