Ariel Roldán
McGill University(CA)
Publications by Year
Research Areas
Cystic Fibrosis Research Advances, HIV Research and Treatment, Advanced biosensing and bioanalysis techniques, Neonatal Respiratory Health Research, Cellular transport and secretion
Most-Cited Works
- → Mechanism-based corrector combination restores ΔF508-CFTR folding and function(2013)386 cited
- → Correction of Both NBD1 Energetics and Domain Interface Is Required to Restore ΔF508 CFTR Folding and Function(2012)289 cited
- → Allosteric folding correction of F508del and rare CFTR mutants by elexacaftor-tezacaftor-ivacaftor (Trikafta) combination(2020)255 cited
- → Structure-guided combination therapy to potently improve the function of mutant CFTRs(2018)138 cited
- → Characterization of a Putative α-Helix across the Capsid-SP1 Boundary That Is Critical for the Multimerization of Human Immunodeficiency Virus Type 1 Gag(2002)102 cited
- → Interplay of Endosomal pH and Ligand Occupancy in Integrin α5β1 Ubiquitination, Endocytic Sorting, and Cell Migration(2015)81 cited
- → Discovery of novel potent ΔF 508‐ CFTR correctors that target the nucleotide binding domain(2013)80 cited
- → Chaperones rescue the energetic landscape of mutant CFTR at single molecule and in cell(2017)69 cited
- → Synergy-Based Small-Molecule Screen Using a Human Lung Epithelial Cell Line Yields ΔF508-CFTR Correctors That Augment VX-809 Maximal Efficacy(2014)65 cited
- → Mutation of the SP1 Sequence Impairs both Multimerization and Membrane-Binding Activities of Human Immunodeficiency Virus Type 1 Gag(2005)51 cited