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Eva Frei | doi.page

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Eva Frei

Publications by Year

Research Areas

Pharmacogenetics and Drug Metabolism, Cancer therapeutics and mechanisms, Carcinogens and Genotoxicity Assessment, Drug-Induced Hepatotoxicity and Protection, Nephrotoxicity and Medicinal Plants

Most-Cited Works

Sudan I is a potential carcinogen for humans: evidence for its metabolic activation and detoxication by human recombinant cytochrome P450 1A1 and liver microsomes.(2002)
→ Native albumin for targeted drug delivery(2010)149 cited
→ Anthracyclines and ellipticines as DNA-damaging anticancer drugs: Recent advances(2011)149 cited
→ The anticancer agent ellipticine on activation by cytochrome P450 forms covalent DNA adducts☆(2001)148 cited
→ Metabolic activation of benzo[a]pyrene in vitro by hepatic cytochrome P450 contrasts with detoxification in vivo: experiments with hepatic cytochrome P450 reductase null mice(2007)142 cited
→ The Anticancer Drug Ellipticine Forms Covalent DNA Adducts, Mediated by Human Cytochromes P450, through Metabolism to 13-Hydroxyellipticine and EllipticineN2-Oxide(2004)133 cited
→

Environmental Pollutant and Potent Mutagen 3-Nitrobenzanthrone Forms DNA Adducts after Reduction by NAD(P)H:Quinone Oxidoreductase and Conjugation by Acetyltransferases and Sulfotransferases in Human Hepatic Cytosols

(2005)

121 cited

→ Human Enzymes Involved in the Metabolic Activation of Carcinogenic Aristolochic Acids: Evidence for Reductive Activation by Cytochromes P450 1A1 and 1A2(2001)120 cited

→ Metabolic activation of carcinogenic aristolochic acid, a risk factor for Balkan endemic nephropathy(2007)118 cited

→ Albumin binding ligands and albumin conjugate uptake by cancer cells(2011)101 cited