Atin Lamsal
Vanderbilt University(US)
Publications by Year
Research Areas
Receptor Mechanisms and Signaling, Neuroscience and Neuropharmacology Research, Nicotinic Acetylcholine Receptors Study, Chemical Synthesis and Analysis, Pharmacological Receptor Mechanisms and Effects
Most-Cited Works
- → Selective Activation of M4Muscarinic Acetylcholine Receptors Reverses MK-801-Induced Behavioral Impairments and Enhances Associative Learning in Rodents(2014)150 cited
- → Potentiation of M1 Muscarinic Receptor Reverses Plasticity Deficits and Negative and Cognitive Symptoms in a Schizophrenia Mouse Model(2015)104 cited
- → Discovery of VU0467485/AZ13713945: An M4 PAM Evaluated as a Preclinical Candidate for the Treatment of Schizophrenia(2016)54 cited
- → Discovery of N-(4-methoxy-7-methylbenzo[d]thiazol-2-yl)isonicatinamide, ML293, as a novel, selective and brain penetrant positive allosteric modulator of the muscarinic 4 (M4) receptor(2012)44 cited
- → Discovery of a selective M4 positive allosteric modulator based on the 3-amino-thieno[2,3-b]pyridine-2-carboxamide scaffold: Development of ML253, a potent and brain penetrant compound that is active in a preclinical model of schizophrenia(2012)41 cited
- → Challenges in the development of an M4 PAM in vivo tool compound: The discovery of VU0467154 and unexpected DMPK profiles of close analogs(2016)40 cited
- → Chemical Modification of the M1Agonist VU0364572 Reveals Molecular Switches in Pharmacology and a Bitopic Binding Mode(2012)36 cited
- → Application of Parallel Multiparametric Cell-Based FLIPR Detection Assays for the Identification of Modulators of the Muscarinic Acetylcholine Receptor 4 (M4)(2015)31 cited
- → Development of a Highly Potent, Novel M5Positive Allosteric Modulator (PAM) Demonstrating CNS Exposure: 1-((1H-Indazol-5-yl)sulfoneyl)-N-ethyl-N-(2-(trifluoromethyl)benzyl)piperidine-4-carboxamide (ML380)(2014)30 cited
- → Discovery of ML326: The first sub-micromolar, selective M5 PAM(2013)29 cited