Ian Hickson
Newcastle University(GB)
Publications by Year
Research Areas
Prostate Cancer Treatment and Research, DNA Repair Mechanisms, Cancer, Lipids, and Metabolism, Estrogen and related hormone effects, Hormonal and reproductive studies
Most-Cited Works
- → Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy(2005)6,589 cited
- → Identification and Characterization of a Novel and Specific Inhibitor of the Ataxia-Telangiectasia Mutated Kinase ATM(2004)1,202 cited
- → AZD8055 Is a Potent, Selective, and Orally Bioavailable ATP-Competitive Mammalian Target of Rapamycin Kinase Inhibitor with In vitro and In vivo Antitumor Activity(2009)793 cited
- → JNJ-26481585, a Novel Second-Generation Oral Histone Deacetylase Inhibitor, Shows Broad-Spectrum Preclinical Antitumoral Activity(2009)231 cited
- → Discovery of 4-{4-[(3R)-3-Methylmorpholin-4-yl]-6-[1-(methylsulfonyl)cyclopropyl]pyrimidin-2-yl}-1H-indole (AZ20): A Potent and Selective Inhibitor of ATR Protein Kinase with Monotherapy in Vivo Antitumor Activity(2013)214 cited
- → Pyranone, Thiopyranone, and Pyridone Inhibitors of Phosphatidylinositol 3-Kinase Related Kinases. Structure−Activity Relationships for DNA-Dependent Protein Kinase Inhibition, and Identification of the First Potent and Selective Inhibitor of the Ataxia Telangiectasia Mutated Kinase(2007)82 cited
- → The discovery and optimisation of pyrido[2,3-d]pyrimidine-2,4-diamines as potent and selective inhibitors of mTOR kinase(2009)79 cited
- → Modulating Androgen Receptor-Driven Transcription in Prostate Cancer with Selective CDK9 Inhibitors(2020)78 cited
- → USP 45 deubiquitylase controls ERCC 1– XPF endonuclease‐mediated DNA damage responses(2014)61 cited
- → O 6-Benzylguanine Potentiates the In Vivo Toxicity and Clastogenicity of Temozolomide and BCNU in Mouse Bone Marrow(1997)59 cited