Vanita Chopra
Harvard University(US)Massachusetts General Hospital(US)
Publications by Year
Research Areas
Genetic Neurodegenerative Diseases, Mitochondrial Function and Pathology, Muscle Physiology and Disorders, Autophagy in Disease and Therapy, Ubiquitin and proteasome pathways
Most-Cited Works
- → The Sirtuin 2 Inhibitor AK-7 Is Neuroprotective in Huntington’s Disease Mouse Models(2012)214 cited
- → Mechanisms of Copper Ion Mediated Huntington's Disease Progression(2007)211 cited
- → The Sirtuin 2 microtubule deacetylase is an abundant neuronal protein that accumulates in the aging CNS(2011)203 cited
- → KEAP1-modifying small molecule reveals muted NRF2 signaling responses in neural stem cells from Huntington's disease patients(2017)137 cited
- → Single-step detection of mutant huntingtin in animal and human tissues: A bioassay for Huntington’s disease(2009)129 cited
- → A small-molecule therapeutic lead for Huntington's disease: Preclinical pharmacology and efficacy of C2-8 in the R6/2 transgenic mouse(2007)109 cited
- → Optogenetic Restoration of Disrupted Slow Oscillations Halts Amyloid Deposition and Restores Calcium Homeostasis in an Animal Model of Alzheimer’s Disease(2017)108 cited
- → Intestinal alkaline phosphatase targets the gut barrier to prevent aging(2020)106 cited
- → Transcriptional modulator H2A histone family, member Y ( H2AFY ) marks Huntington disease activity in man and mouse(2011)102 cited
- → The mTOR kinase inhibitor Everolimus decreases S6 kinase phosphorylation but fails to reduce mutant huntingtin levels in brain and is not neuroprotective in the R6/2 mouse model of Huntington's disease(2010)96 cited