Nilantha Sirisoma
Publications by Year
Research Areas
Synthesis and biological activity, Synthesis and Characterization of Heterocyclic Compounds, Cancer therapeutics and mechanisms, Quinazolinone synthesis and applications, Synthesis of Tetrazole Derivatives
Most-Cited Works
- → The natural polyamine spermine functions directly as a free radical scavenger(1998)676 cited
- → α-Thujone (the active component of absinthe): γ-Aminobutyric acid type A receptor modulation and metabolic detoxification(2000)352 cited
- → A role for transferrin receptor in triggering apoptosis when targeted with gambogic acid(2005)211 cited
- → MPC-6827: A Small-Molecule Inhibitor of Microtubule Formation That Is Not a Substrate for Multidrug Resistance Pumps(2007)125 cited
- → Discovery of N-(4-Methoxyphenyl)-N,2-dimethylquinazolin-4-amine, a Potent Apoptosis Inducer and Efficacious Anticancer Agent with High Blood Brain Barrier Penetration(2009)122 cited
- → Discovery of 1-benzoyl-3-cyanopyrrolo[1,2-a]quinolines as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. Part 1: Structure–activity relationships of the 1- and 3-positions(2008)82 cited
- → Detoxification of α- and β-Thujones (the Active Ingredients of Absinthe): Site Specificity and Species Differences in Cytochrome P450 Oxidation in Vitro and in Vivo(2001)79 cited
- → Discovery of 2-Chloro-N-(4-methoxyphenyl)-N-methylquinazolin-4-amine (EP128265, MPI-0441138) as a Potent Inducer of Apoptosis with High In Vivo Activity(2008)65 cited
- → Discovery of N-methyl-4-(4-methoxyanilino)quinazolines as potent apoptosis inducers. Structure–activity relationship of the quinazoline ring(2010)49 cited
- → Discovery of substituted 4-anilino-2-(2-pyridyl)pyrimidines as a new series of apoptosis inducers using a cell- and caspase-based high throughput screening assay. Part 1: Structure–activity relationships of the 4-anilino group(2006)43 cited