Benedetta Crescenzi
Galapagos (France)(FR)
Publications by Year
Research Areas
HIV/AIDS drug development and treatment, Hepatitis C virus research, HIV Research and Treatment, Chemical Synthesis and Analysis, Biochemical and Molecular Research
Most-Cited Works
- → Discovery of Raltegravir, a Potent, Selective Orally Bioavailable HIV-Integrase Inhibitor for the Treatment of HIV-AIDS Infection(2008)627 cited
- → Discovery of MK-5172, a Macrocyclic Hepatitis C Virus NS3/4a Protease Inhibitor(2012)201 cited
- → Discovery and Optimization of an Azetidine Chemical Series As a Free Fatty Acid Receptor 2 (FFA2) Antagonist: From Hit to Clinic(2014)109 cited
- → Discovery and Synthesis of HIV Integrase Inhibitors: Development of Potent and Orally Bioavailable N-Methyl Pyrimidones(2007)67 cited
- → Discovery of (7R)-14-Cyclohexyl-7-{[2-(dimethylamino)ethyl](methyl) amino}-7,8-dihydro-6H-indolo[1,2-e][1,5]benzoxazocine-11-carboxylic Acid (MK-3281), a Potent and Orally Bioavailable Finger-Loop Inhibitor of the Hepatitis C Virus NS5B Polymerase(2010)66 cited
- → Design and Synthesis of Bicyclic Pyrimidinones as Potent and Orally Bioavailable HIV-1 Integrase Inhibitors(2008)52 cited
- → Synthesis of a hexahydropyrimido[1,2-a]azepine-2-carboxamide derivative useful as an HIV integrase inhibitor(2007)19 cited
- → Oxidation of 3-arylisochromans by dimethyldioxirane. An easy route to substituted 3-arylisocoumarins(1999)19 cited
- → Inhibitors of the Hepatitis C Virus NS3 Protease with Basic Amine Functionality at the P3-Amino Acid N-Terminus: Discovery and Optimization of a New Series of P2−P4 Macrocycles(2009)16 cited
- → Dihydroxy-pyrimidine and N-methylpyrimidone HIV-integrase inhibitors: Improving cell based activity by the quaternarization of a chiral center(2009)11 cited