Simon P. Fletcher
Gilead Sciences (United States)(US)
Publications by Year
Research Areas
Hepatitis B Virus Studies, Hepatitis C virus research, Liver Disease Diagnosis and Treatment, Immune Response and Inflammation, Immunotherapy and Immune Responses
Most-Cited Works
- → A prokaryotic-like mode of cytoplasmic eukaryotic ribosome binding to the initiation codon during internal translation initation of hepatitis C and classical swine fever virus RNAs(1998)720 cited
- → Hepatitis B virus X protein identifies the Smc5/6 complex as a host restriction factor(2016)528 cited
- → PD-1 blockade partially recovers dysfunctional virus–specific B cells in chronic hepatitis B infection(2018)271 cited
- → Isatoribine, an Agonist of TLR7, Reduces Plasma Virus Concentration in Chronic Hepatitis C Infection *(2005)236 cited
- → Sustained efficacy and seroconversion with the Toll-like receptor 7 agonist GS-9620 in the Woodchuck model of chronic hepatitis B(2015)202 cited
- → The Smc5/6 Complex Restricts HBV when Localized to ND10 without Inducing an Innate Immune Response and Is Counteracted by the HBV X Protein Shortly after Infection(2017)150 cited
- → Pestivirus Internal Ribosome Entry Site (IRES) Structure and Function: Elements in the 5′ Untranslated Region Important for IRES Function(2002)112 cited
- → An immune dysfunction score for stratification of patients with acute infection based on whole-blood gene expression(2022)101 cited
- → Transcriptomic analysis of the woodchuck model of chronic hepatitis B(2012)100 cited
- → Toll-like receptor 7 agonist GS-9620 induces prolonged inhibition of HBV via a type I interferon-dependent mechanism(2017)96 cited