Keith Mikule
Publications by Year
Research Areas
PARP inhibition in cancer therapy, Advanced Breast Cancer Therapies, Microtubule and mitosis dynamics, BRCA gene mutations in cancer, DNA Repair Mechanisms
Most-Cited Works
- → Suppression of cancer relapse and metastasis by inhibiting cancer stemness(2015)453 cited
- → Centrosome control of the cell cycle(2005)311 cited
- → Loss of centrosome integrity induces p38—p53—p21-dependent G1—S arrest(2006)311 cited
- → Niraparib activates interferon signaling and potentiates anti-PD-1 antibody efficacy in tumor models(2019)255 cited
- → A comparative pharmacokinetic study of PARP inhibitors demonstrates favorable properties for niraparib efficacy in preclinical tumor models(2018)177 cited
- → Synthetic Lethality of PARP Inhibitors in Combination with MYC Blockade Is Independent of BRCA Status in Triple-Negative Breast Cancer(2017)144 cited
- → Discovery and Mechanistic Study of a Small Molecule Inhibitor for Motor Protein KIFC1(2013)121 cited
- → Growth Cone Collapse Induced by Semaphorin 3A Requires 12/15-Lipoxygenase(2002)64 cited
- → Discovery of AZ0108, an orally bioavailable phthalazinone PARP inhibitor that blocks centrosome clustering(2015)62 cited
- → Pharmacological Inhibition of PARP6 Triggers Multipolar Spindle Formation and Elicits Therapeutic Effects in Breast Cancer(2018)45 cited