John P. Giddens
Revolution Medicines (United States)(US)
Publications by Year
Research Areas
Glycosylation and Glycoproteins Research, Monoclonal and Polyclonal Antibodies Research, Carbohydrate Chemistry and Synthesis, Galectins and Cancer Biology, HIV Research and Treatment
Most-Cited Works
- → Modulating IgG effector function by Fc glycan engineering(2017)320 cited
- → Chemoenzymatic Glycoengineering of Intact IgG Antibodies for Gain of Functions(2012)308 cited
- → Sialylation of IgG Fc domain impairs complement-dependent cytotoxicity(2015)261 cited
- → Structural Characterization of Anti-Inflammatory Immunoglobulin G Fc Proteins(2014)153 cited
- → Glycoengineering of Antibodies for Modulating Functions(2019)132 cited
- → Glycosynthase Mutants of Endoglycosidase S2 Show Potent Transglycosylation Activity and Remarkably Relaxed Substrate Specificity for Antibody Glycosylation Remodeling(2016)119 cited
- → Site-selective chemoenzymatic glycoengineering of Fab and Fc glycans of a therapeutic antibody(2018)96 cited
- → Endo-F3 Glycosynthase Mutants Enable Chemoenzymatic Synthesis of Core-fucosylated Triantennary Complex Type Glycopeptides and Glycoproteins(2016)89 cited
- → Crystal structure ofStreptococcus pyogenesEndoS, an immunomodulatory endoglycosidase specific for human IgG antibodies(2014)67 cited
- → Chemoenzymatic Fc Glycosylation via Engineered Aldehyde Tags(2014)65 cited