Jonathan Bauman
Pfizer (United States)(US)
Publications by Year
Research Areas
Pharmacogenetics and Drug Metabolism, Drug-Induced Hepatotoxicity and Protection, Drug Transport and Resistance Mechanisms, Crystallization and Solubility Studies, X-ray Diffraction in Crystallography
Most-Cited Works
- → Structural Alert/Reactive Metabolite Concept as Applied in Medicinal Chemistry to Mitigate the Risk of Idiosyncratic Drug Toxicity: A Perspective Based on the Critical Examination of Trends in the Top 200 Drugs Marketed in the United States(2011)688 cited
- → On-resin N-methylation of cyclic peptides for discovery of orally bioavailable scaffolds(2011)376 cited
- → Discovery of a JAK3-Selective Inhibitor: Functional Differentiation of JAK3-Selective Inhibition over pan-JAK or JAK1-Selective Inhibition(2016)191 cited
- → Optimized Assays for Human UDP-Glucuronosyltransferase (UGT) Activities: Altered Alamethicin Concentration and Utility to Screen for UGT Inhibitors(2012)149 cited
- → Kinetics of Acetaminophen Glucuronidation by UDP-Glucuronosyltransferases 1A1, 1A6, 1A9 and 2B15. Potential Implications in Acetaminophen−Induced Hepatotoxicity(2006)134 cited
- → Comparison of the Bioactivation Potential of the Antidepressant and Hepatotoxin Nefazodone with Aripiprazole, a Structural Analog and Marketed Drug(2008)83 cited
- → Identification of Cyanamide-Based Janus Kinase 3 (JAK3) Covalent Inhibitors(2018)74 cited
- → Determination of Degradation Pathways and Kinetics of Acyl Glucuronides by NMR Spectroscopy(2007)67 cited
- → Immune-Mediated Agranulocytosis Caused by the Cocaine Adulterant Levamisole: A Case for Reactive Metabolite(s) Involvement(2012)66 cited
- → Reaction Phenotyping in Drug Discovery: Moving Forward with Confidence?(2003)64 cited