Merrill Ayres
Amgen (United States)(US)
Publications by Year
Research Areas
NF-κB Signaling Pathways, Receptor Mechanisms and Signaling, Protein Kinase Regulation and GTPase Signaling, Immune Response and Inflammation, Microtubule and mitosis dynamics
Most-Cited Works
- → Crystal Structures of IRAK-4 Kinase in Complex with Inhibitors: A Serine/Threonine Kinase with Tyrosine as a Gatekeeper(2006)145 cited
- → Structural and Functional Characterization of the JH2 Pseudokinase Domain of JAK Family Tyrosine Kinase 2 (TYK2)(2015)99 cited
- → Inhibiting NF-κB-inducing kinase (NIK): Discovery, structure-based design, synthesis, structure–activity relationship, and co-crystal structures(2013)71 cited
- → Discovery of AMG 925, a FLT3 and CDK4 Dual Kinase Inhibitor with Preferential Affinity for the Activated State of FLT3(2014)70 cited
- → The Human Pim-1 Gene Is Selectively Transcribed in Different Hemato-Lymphoid Cell Lines in Spite of a G+C-Rich Housekeeping Promoter(1990)62 cited
- → Structure of the Nuclear Factor κB-inducing Kinase (NIK) Kinase Domain Reveals a Constitutively Active Conformation(2012)57 cited
- → An ultrasensitive high-throughput electrochemiluminescence immunoassay for the Cdc42-associated protein tyrosine kinase ACK1(2007)9 cited