William J. Meilandt
Neuroscience Institute(IT)
Publications by Year
Research Areas
Alzheimer's disease research and treatments, Neuroinflammation and Neurodegeneration Mechanisms, Neuroscience and Neuropharmacology Research, Computational Drug Discovery Methods, Neurological Disease Mechanisms and Treatments
Most-Cited Works
- → Diverse Brain Myeloid Expression Profiles Reveal Distinct Microglial Activation States and Aspects of Alzheimer’s Disease Not Evident in Mouse Models(2018)694 cited
- → Changes in the Synaptic Proteome in Tauopathy and Rescue of Tau-Induced Synapse Loss by C1q Antibodies(2018)539 cited
- → Complement C3 Is Activated in Human AD Brain and Is Required for Neurodegeneration in Mouse Models of Amyloidosis and Tauopathy(2019)454 cited
- → Therapeutic bispecific antibodies cross the blood-brain barrier in nonhuman primates(2014)359 cited
- → Trem2 restrains the enhancement of tau accumulation and neurodegeneration by β-amyloid pathology(2021)339 cited
- → A Therapeutic Antibody Targeting BACE1 Inhibits Amyloid-β Production in Vivo(2011)276 cited
- → Addressing Safety Liabilities of TfR Bispecific Antibodies That Cross the Blood-Brain Barrier(2013)261 cited
- → Trem2 Deletion Reduces Late-Stage Amyloid Plaque Accumulation, Elevates the Aβ42:Aβ40 Ratio, and Exacerbates Axonal Dystrophy and Dendritic Spine Loss in the PS2APP Alzheimer's Mouse Model(2020)226 cited
- → Integrative in situ mapping of single-cell transcriptional states and tissue histopathology in a mouse model of Alzheimer’s disease(2023)208 cited
- → Loss of dual leucine zipper kinase signaling is protective in animal models of neurodegenerative disease(2017)160 cited