Dirk Heckl
Goethe University Frankfurt(DE)
Publications by Year
Research Areas
Acute Myeloid Leukemia Research, RNA Interference and Gene Delivery, Chronic Myeloid Leukemia Treatments, Protein Degradation and Inhibitors, Cancer-related molecular mechanisms research
Most-Cited Works
- → Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells(2013)5,440 cited
- → Lenalidomide Causes Selective Degradation of IKZF1 and IKZF3 in Multiple Myeloma Cells(2013)1,799 cited
- → Single-cell RNA-seq reveals changes in cell cycle and differentiation programs upon aging of hematopoietic stem cells(2015)849 cited
- → Refined sgRNA efficacy prediction improves large- and small-scale CRISPR–Cas9 applications(2017)312 cited
- → Core Circadian Clock Genes Regulate Leukemia Stem Cells in AML(2016)271 cited
- → Gli1+ Mesenchymal Stromal Cells Are a Key Driver of Bone Marrow Fibrosis and an Important Cellular Therapeutic Target(2017)262 cited
- → Role of Casein Kinase 1A1 in the Biology and Targeted Therapy of del(5q) MDS(2014)182 cited
- → Depletion of Jak2V617F myeloproliferative neoplasm-propagating stem cells by interferon-α in a murine model of polycythemia vera(2013)170 cited
- → Pharmacological GLI2 inhibition prevents myofibroblast cell-cycle progression and reduces kidney fibrosis(2015)165 cited
- → The non-coding RNA landscape of human hematopoiesis and leukemia(2017)162 cited