Nobunao Wakabayashi
Fred Hutch Cancer Center(US)
Publications by Year
Research Areas
Genomics, phytochemicals, and oxidative stress, Glutathione Transferases and Polymorphisms, Mitochondrial Function and Pathology, Adipose Tissue and Metabolism, Air Quality and Health Impacts
Most-Cited Works
- → Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain(1999)3,543 cited
- → Cell Survival Responses to Environmental Stresses Via the Keap1-Nrf2-ARE Pathway(2006)3,541 cited
- → Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants(2002)1,909 cited
- → Protection against electrophile and oxidant stress by induction of the phase 2 response: Fate of cysteines of the Keap1 sensor modified by inducers(2004)960 cited
- → Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation(2003)884 cited
- → Keap1 regulates both cytoplasmic‐nuclear shuttling and degradation of Nrf2 in response to electrophiles(2003)818 cited