Stuart P. Romeril
Acorn(US)
Publications by Year
Research Areas
Marine Sponges and Natural Products, Synthetic Organic Chemistry Methods, Epigenetics and DNA Methylation, RNA modifications and cancer, Chemical synthesis and alkaloids
Most-Cited Works
- → Discovery of 7-Methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a Potent and Selective First-in-Class Inhibitor of Protein Kinase R (PKR)-like Endoplasmic Reticulum Kinase (PERK)(2012)608 cited
- → On the Mechanism of the Palladium(II)-Catalyzed Decarboxylative Olefination of Arene Carboxylic Acids. Crystallographic Characterization of Non-Phosphine Palladium(II) Intermediates and Observation of Their Stepwise Transformation in Heck-like Processes(2005)426 cited
- → Identification of Potent, Selective, Cell-Active Inhibitors of the Histone Lysine Methyltransferase EZH2(2012)375 cited
- → Discovery of a first-in-class reversible DNMT1-selective inhibitor with improved tolerability and efficacy in acute myeloid leukemia(2021)262 cited
- → Discovery of GSK2656157: An Optimized PERK Inhibitor Selected for Preclinical Development(2013)226 cited
- → Structure-Based Design of Potent and Selective 3-Phosphoinositide-Dependent Kinase-1 (PDK1) Inhibitors(2011)54 cited
- → Studies toward the Total Synthesis of the Cytotoxic Sponge Alkaloid Pyrinodemin A(2001)33 cited
- → Investigation into the absolute stereochemistry of the marine sponge alkaloid pyrinodemin A(2003)22 cited
- → Synthesis of a possible structure of pyrinodemin A(2002)19 cited
- → On the synthesis of pyrinodemin A. Part 1: The location of the olefin(2004)16 cited