Wanda DePinto
Roche (Switzerland)(CH)Rutgers New Jersey Medical School
Publications by Year
Research Areas
Cancer-related Molecular Pathways, Microtubule and mitosis dynamics, Advanced Breast Cancer Therapies, Cancer therapeutics and mechanisms, Quinazolinone synthesis and applications
Most-Cited Works
- → Discovery of [4-Amino-2-(1-methanesulfonylpiperidin-4-ylamino)pyrimidin-5-yl](2,3-difluoro-6- methoxyphenyl)methanone (R547), A Potent and Selective Cyclin-Dependent Kinase Inhibitor with Significant in Vivo Antitumor Activity(2006)116 cited
- → In vitro and in vivo activity of R547: a potent and selective cyclin-dependent kinase inhibitor currently in phase I clinical trials(2006)102 cited
- → A new series of potent oxindole inhibitors of CDK2(2004)51 cited
- → Synthesis of Potent Oxindole CDK2 Inhibitors(2003)48 cited
- → Inhibition of S/G2 Phase CDK4 Reduces Mitotic Fidelity(2006)31 cited
- → A phase I study of R547, a novel, selective inhibitor of cell cycle and transcriptional cyclin dependent kinases (CDKs)(2007)29 cited
- → 3,5,6-Trisubstituted naphthostyrils as CDK2 inhibitors(2003)29 cited
- → Preclinical biomarkers for a cyclin-dependent kinase inhibitor translate to candidate pharmacodynamic biomarkers in phase I patients(2009)24 cited
- Design, synthesis of 1,4-cyclohexyldiamine substituted diaminopyrimidines as selective inhibitors of CDK1, CDK2 and CDK4 and their in vitro and in vivo evaluation(2005)
- → The structure of cyclin dependent kinase 2 (CKD2) with a trisubstituted naphthostyril inhibitor(2003)1 cited