Craig M. Goodwin
University of North Carolina at Chapel Hill(US)
Publications by Year
Research Areas
Advanced Breast Cancer Therapies, Pancreatic and Hepatic Oncology Research, Colorectal Cancer Treatments and Studies, Cancer-related Molecular Pathways, PI3K/AKT/mTOR signaling in cancer
Most-Cited Works
- → Drugging an undruggable pocket on KRAS(2019)419 cited
- → Atypical KRASG12R Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer(2019)213 cited
- → Combination Therapies with CDK4/6 Inhibitors to Treat KRAS- Mutant Pancreatic Cancer(2022)147 cited
- → Discovery of 2-Indole-acylsulfonamide Myeloid Cell Leukemia 1 (Mcl-1) Inhibitors Using Fragment-Based Methods(2016)144 cited
- → Myeloid cell leukemia-1 is an important apoptotic survival factor in triple-negative breast cancer(2015)105 cited
- → Low-Dose Vertical Inhibition of the RAF-MEK-ERK Cascade Causes Apoptotic Death of KRAS Mutant Cancers(2020)103 cited
- → Discovery of Tricyclic Indoles That Potently Inhibit Mcl-1 Using Fragment-Based Methods and Structure-Based Design(2015)95 cited
- → Defining the KRAS- and ERK-dependent transcriptome in KRAS-mutant cancers(2024)91 cited
- → Discovery and biological characterization of potent myeloid cell leukemia‐1 inhibitors(2016)61 cited
- → Functional and biological heterogeneity of KRAS Q61 mutations(2022)41 cited