Linda Bao
Publications by Year
Research Areas
PI3K/AKT/mTOR signaling in cancer, Protein Kinase Regulation and GTPase Signaling, Drug Solubulity and Delivery Systems, Phytochemicals and Antioxidant Activities, Advancements in Transdermal Drug Delivery
Most-Cited Works
- → Discovery of a Potent, Selective, and Orally Available Class I Phosphatidylinositol 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Kinase Inhibitor (GDC-0980) for the Treatment of Cancer(2011)215 cited
- → Discovery and Biological Profiling of Potent and Selective mTOR Inhibitor GDC-0349(2012)46 cited
- → In Vitro and In Vivo Evaluation of Amorphous Solid Dispersions Generated by Different Bench-Scale Processes, Using Griseofulvin as a Model Compound(2013)32 cited
- → Discovery of TRPA1 Antagonist GDC-6599: Derisking Preclinical Toxicity and Aldehyde Oxidase Metabolism with a Potential First-in-Class Therapy for Respiratory Disease(2024)20 cited
- → On Demand Bioorthogonal Switching of an Antibody-Conjugated SPECT Probe to a Cytotoxic Payload: from Imaging to Therapy(2024)17 cited
- → Optimization of a Novel DEL Hit That Binds in the Cbl-b SH2 Domain and Blocks Substrate Binding(2024)10 cited
- → Solubilization of a Poorly Soluble B-Raf (Rapidly Accelerated Fibrosarcoma) Inhibitor: From Theory to Application(2017)1 cited
- → Abstract 2787: Discovery of GDC-0980, a selective PI3K/mTOR inhibitor in clinical trials(2011)