Derek E. Piper
Amgen (United States)(US)
Publications by Year
Research Areas
Monoclonal and Polyclonal Antibodies Research, Hepatitis C virus research, Lipoproteins and Cardiovascular Health, RNA and protein synthesis mechanisms, Drug Transport and Resistance Mechanisms
Most-Cited Works
- → A proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates(2009)407 cited
- → Structure of a HoxB1–Pbx1 Heterodimer Bound to DNA(1999)327 cited
- → The Structure of GABPα/β: An ETS Domain- Ankyrin Repeat Heterodimer Bound to DNA(1998)286 cited
- → The Crystal Structure of PCSK9: A Regulator of Plasma LDL-Cholesterol(2007)239 cited
- → Hepatocyte growth factor is a preferred in vitro substrate for human hepsin, a membrane-anchored serine protease implicated in prostate and ovarian cancers(2005)194 cited
- → Molecular basis of PCSK9 function(2008)193 cited
- → SAR and Mode of Action of Novel Non-Nucleoside Inhibitors of Hepatitis C NS5b RNA Polymerase(2006)126 cited
- → Discovery of AMG 925, a FLT3 and CDK4 Dual Kinase Inhibitor with Preferential Affinity for the Activated State of FLT3(2014)70 cited
- → The high-resolution crystal structure of human LCAT(2015)45 cited
- → Novel Inhibitors of Hepatitis C Virus RNA-dependent RNA Polymerases(2006)40 cited