Dirk B. Mendel
Spark Therapeutics (United States)(US)Stanford University(US)
Publications by Year
Research Areas
Influenza Virus Research Studies, Receptor Mechanisms and Signaling, Chemical Synthesis and Analysis, Estrogen and related hormone effects, Monoclonal and Polyclonal Antibodies Research
Most-Cited Works
- In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic/pharmacodynamic relationship.(2003)
- → Influenza Neuraminidase Inhibitors Possessing a Novel Hydrophobic Interaction in the Enzyme Active Site: Design, Synthesis, and Structural Analysis of Carbocyclic Sialic Acid Analogues with Potent Anti-Influenza Activity(1997)1,091 cited
- → BRG1 contains a conserved domain of the SWI2/SNF2 family necessary for normal mitotic growth and transcription(1993)678 cited
- A selective small molecule inhibitor of c-Met kinase inhibits c-Met-dependent phenotypes in vitro and exhibits cytoreductive antitumor activity in vivo.(2003)
- → The H274Y mutation in the influenza A/H1N1 neuraminidase active site following oseltamivir phosphate treatment leave virus severely compromised both in vitro and in vivo(2002)380 cited
- → Cytotoxicity of Antiviral Nucleotides Adefovir and Cidofovir Is Induced by the Expression of Human Renal Organic Anion Transporter 1(2000)354 cited
- → The Antiviral Nucleotide Analogs Cidofovir and Adefovir Are Novel Substrates for Human and Rat Renal Organic Anion Transporter 1