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Joaquı́n M. Espinosa | doi.page

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Joaquı́n M. Espinosa

University of Colorado Anschutz Medical Campus(US)University of Colorado Denver(US)

Publications by Year

Research Areas

Cancer-related Molecular Pathways, Ubiquitin and proteasome pathways, RNA modifications and cancer, Protein Degradation and Inhibitors, Epigenetics and DNA Methylation

Most-Cited Works

→ The Histone Deacetylase Sirt6 Regulates Glucose Homeostasis via Hif1α(2010)986 cited
→ Transcriptional regulation by hypoxia inducible factors(2013)781 cited
→ Mechanisms of transcriptional regulation by p53(2017)450 cited
→ Transcriptional Regulation by p53 through Intrinsic DNA/Chromatin Binding and Site-Directed Cofactor Recruitment(2001)443 cited
→ Trisomy 21 consistently activates the interferon response(2016)367 cited
→ CDK8 is a positive regulator of transcriptional elongation within the serum response network(2010)366 cited

→ HIF1A Employs CDK8-Mediator to Stimulate RNAPII Elongation in Response to Hypoxia(2013)

352 cited

→ RNA polymerase II pauses and associates with pre-mRNA processing factors at both ends of genes(2007)340 cited

→ Gene-specific requirement for P-TEFb activity and RNA polymerase II phosphorylation within the p53 transcriptional program(2006)267 cited

→ p53 Functions through Stress- and Promoter-Specific Recruitment of Transcription Initiation Components before and after DNA Damage(2003)258 cited