Yoshiharu Mizui
Publications by Year
Research Areas
RNA Research and Splicing, RNA modifications and cancer, Synthetic Organic Chemistry Methods, RNA and protein synthesis mechanisms, Microbial Natural Products and Biosynthesis
Most-Cited Works
- → Splicing factor SF3b as a target of the antitumor natural product pladienolide(2007)654 cited
- → H3B-8800, an orally available small-molecule splicing modulator, induces lethality in spliceosome-mutant cancers(2018)500 cited
- → Cancer-Associated SF3B1 Hotspot Mutations Induce Cryptic 3′ Splice Site Selection through Use of a Different Branch Point(2015)458 cited
- → Phase I Pharmacokinetic and Pharmacodynamic Study of the First-in-Class Spliceosome Inhibitor E7107 in Patients with Advanced Solid Tumors(2013)248 cited
- → Pladienolides, New Substances from Culture of Streptomyces platensis Mer-11107 III. In Vitro and In Vivo Antitumor Activities(2004)187 cited
- → Biological validation that SF3b is a target of the antitumor macrolide pladienolide(2011)179 cited
- → Splicing modulators act at the branch point adenosine binding pocket defined by the PHF5A–SF3b complex(2017)148 cited
- → Pladienolides, New Substances from Culture of Streptomyces platensis Mer-11107 I. Taxonomy, Fermentation, Isolation and Screening(2004)129 cited
- → Pladienolides, New Substances from Culture of Streptomyces platensis Mer-11107 II. Physico-chemical Properties and Structure Elucidation(2004)93 cited
- → Total Synthesis of the Potent Antitumor Macrolides Pladienolide B and D(2007)93 cited