Misaki Homma
Takeda (Japan)(JP)
Publications by Year
Research Areas
Crystallization and Solubility Studies, X-ray Diffraction in Crystallography, Cancer therapeutics and mechanisms, Synthesis and Reactivity of Heterocycles, Parkinson's Disease Mechanisms and Treatments
Most-Cited Works
- → Visualizing and Modulating Mitophagy for Therapeutic Studies of Neurodegeneration(2020)170 cited
- → Discovery of Potent Mcl-1/Bcl-xL Dual Inhibitors by Using a Hybridization Strategy Based on Structural Analysis of Target Proteins(2013)108 cited
- → Molecular mechanism and potential target indication of TAK-931, a novel CDC7-selective inhibitor(2019)67 cited
- → Discovery of a Novel, Highly Potent, and Selective Thieno[3,2-d]pyrimidinone-Based Cdc7 Inhibitor with a Quinuclidine Moiety (TAK-931) as an Orally Active Investigational Antitumor Agent(2020)22 cited
- → Identification of a new class of potent Cdc7 inhibitors designed by putative pharmacophore model: Synthesis and biological evaluation of 2,3-dihydrothieno[3,2-d]pyrimidin-4(1H)-ones(2017)16 cited
- → 2-Aminomethylthieno[3,2-d]pyrimidin-4(3H)-ones bearing 3-methylpyrazole hinge binding moiety: Highly potent, selective, and time-dependent inhibitors of Cdc7 kinase(2017)16 cited
- → Novel beta-glucocerebrosidase chaperone compounds identified from cell-based screening reduce pathologically accumulated glucosylsphingosine in iPS-derived neuronal cells(2023)10 cited
- → A simple and widely applicable hit validation strategy for protein–protein interaction inhibitors based on a quantitative ligand displacement assay(2014)2 cited
- → CCDC 1918344: Experimental Crystal Structure Determination(2020)
- → CCDC 1918342: Experimental Crystal Structure Determination(2020)