Yun-Chou Tan
Roche (Switzerland)(CH)Roche (United States)(US)La Roche College(US)
Publications by Year
Research Areas
Melanoma and MAPK Pathways, Synthesis and biological activity, Quinazolinone synthesis and applications, Crystallization and Solubility Studies, Organometallic Compounds Synthesis and Characterization
Most-Cited Works
- → Discovery of 6-(2,4-Difluorophenoxy)-2-[3-hydroxy-1-(2-hydroxyethyl)propylamino]-8-methyl-8H-pyrido[2,3-d]pyrimidin-7-one (Pamapimod) and 6-(2,4-Difluorophenoxy)-8-methyl-2-(tetrahydro-2H-pyran-4-ylamino)pyrido[2,3-d]pyrimidin-7(8H)-one (R1487) as Orally Bioavailable and Highly Selective Inhibitors of p38α Mitogen-Activated Protein Kinase(2011)74 cited
- → Pyrrolopyrazines as Selective Spleen Tyrosine Kinase Inhibitors(2013)39 cited
- → Discovery of N-[4-[6-tert-Butyl-5-methoxy-8-(6-methoxy-2-oxo-1H-pyridin-3-yl)-3-quinolyl]phenyl]methanesulfonamide (RG7109), a Potent Inhibitor of the Hepatitis C Virus NS5B Polymerase(2013)31 cited
- → Discovery of potent and bioavailable GSK-3β inhibitors(2010)30 cited
- → Development of amino-pyrimidine inhibitors of c-Jun N-terminal kinase (JNK): Kinase profiling guided optimization of a 1,2,3-benzotriazole lead(2012)27 cited
- → Synthesis and Coordination Chemistry of 2,6-Bis(diphenylphosphinomethyl)phenol P,P‘-Dioxides(2001)23 cited
- → Synthesis and Coordination Chemistry of 1,3-Bis(diphenylphosphinomethyl)benzene P,P‘-Dioxide(2001)22 cited
- → Discovery of a novel series of 4-quinolone JNK inhibitors(2012)19 cited
- → Development of indole/indazole-aminopyrimidines as inhibitors of c-Jun N-terminal kinase (JNK): Optimization for JNK potency and physicochemical properties(2013)18 cited
- → Synthesis of 7,12-Dihydropyridopyrroloindoles (Azapyridodiindoles) via the Fischer Indole Cyclization. A Search for Water Soluble Benzodiazepine Receptor Ligands.(1988)8 cited