Denis E. Ryono
Bristol-Myers Squibb (United States)(US)
Publications by Year
Research Areas
Chemical Synthesis and Analysis, Peptidase Inhibition and Analysis, Receptor Mechanisms and Signaling, Protein Hydrolysis and Bioactive Peptides, Neuropeptides and Animal Physiology
Most-Cited Works
- → Preparation of peptidic α-hydroxy phosphonates a new class of transition state analog renin inhibitors(1990)237 cited
- → Dual Metalloprotease Inhibitors: Mercaptoacetyl-Based Fused Heterocyclic Dipeptide Mimetics as Inhibitors of Angiotensin-Converting Enzyme and Neutral Endopeptidase(1997)198 cited
- → .alpha.-Hydroxy Phosphinyl-Based Inhibitors of Human Renin(1995)190 cited
- → Design and Synthesis of N-[(4-Methoxyphenoxy)carbonyl]-N-[[4-[2-(5- methyl-2-phenyl-4-oxazolyl)ethoxy]phenyl]methyl]glycine [Muraglitazar/BMS-298585], a Novel Peroxisome Proliferator-Activated Receptor α/γ Dual Agonist with Efficacious Glucose and Lipid-Lowering Activities(2004)108 cited
- → Peptidic α-hydroxy phosphinyls C-terminal modification methodology(1990)102 cited
- → Muraglitazar, a Novel Dual (α/γ) Peroxisome Proliferator–Activated Receptor Activator, Improves Diabetes and Other Metabolic Abnormalities and Preserves β-Cell Function in db/db Mice(2006)80 cited
- → Activated ketone based inhibitors of human renin(1993)65 cited
- → Dual Metalloprotease Inhibitors. 6. Incorporation of Bicyclic and Substituted Monocyclic Azepinones as Dipeptide Surrogates in Angiotensin-Converting Enzyme/Neutral Endopeptidase Inhibitors(1996)60 cited
- → Thyroid receptor ligands. Part 2: Thyromimetics with improved selectivity for the thyroid hormone receptor beta(2004)52 cited
- → Angiotensin-converting enzyme inhibitors: importance of the amide carbonyl of mercaptoacyl amino acids for hydrogen bonding to the enzyme(1982)51 cited