Olivier Mirguet
Eurofins (France)(FR)
Publications by Year
Research Areas
Protein Degradation and Inhibitors, Asymmetric Synthesis and Catalysis, Multiple Myeloma Research and Treatments, Chemical synthesis and alkaloids, Synthetic Organic Chemistry Methods
Most-Cited Works
- → Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia(2011)1,506 cited
- → Discovery and Characterization of Small Molecule Inhibitors of the BET Family Bromodomains(2011)334 cited
- → Discovery of Epigenetic Regulator I-BET762: Lead Optimization to Afford a Clinical Candidate Inhibitor of the BET Bromodomains(2013)302 cited
- → Identification of a novel series of BET family bromodomain inhibitors: Binding mode and profile of I-BET151 (GSK1210151A)(2012)207 cited
- → The Discovery of I-BET726 (GSK1324726A), a Potent Tetrahydroquinoline ApoA1 Up-Regulator and Selective BET Bromodomain Inhibitor(2014)187 cited
- → Kynurenine-3-monooxygenase inhibition prevents multiple organ failure in rodent models of acute pancreatitis(2016)157 cited
- → From ApoA1 upregulation to BET family bromodomain inhibition: Discovery of I-BET151(2012)118 cited
- → A Diverted Total Synthesis of Mycolactone Analogues: An Insight into Buruli Ulcer Toxins(2011)62 cited
- → Comparison of Soluble Guanylate Cyclase Stimulators and Activators in Models of Cardiovascular Disease Associated with Oxidative Stress(2012)60 cited
- → Deep generative models for ligand‐based de novo design applied to multi‐parametric optimization(2022)60 cited