Marie Wetzel
Helmholtz Institute for Pharmaceutical Research Saarland(DE)Saarland University(DE)
Publications by Year
Research Areas
Hormonal Regulation and Hypertension, Estrogen and related hormone effects, Steroid Chemistry and Biochemistry, Pharmacogenetics and Drug Metabolism, Organic Chemistry Cycloaddition Reactions
Most-Cited Works
- → 17β-Hydroxysteroid dehydrogenases (17β-HSDs) as therapeutic targets: Protein structures, functions, and recent progress in inhibitor development(2010)209 cited
- → New Drug-Like Hydroxyphenylnaphthol Steroidomimetics As Potent and Selective 17β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors for the Treatment of Estrogen-Dependent Diseases(2010)53 cited
- → Introduction of an Electron Withdrawing Group on the Hydroxyphenylnaphthol Scaffold Improves the Potency of 17β-Hydroxysteroid Dehydrogenase Type 2 (17β-HSD2) Inhibitors(2011)47 cited
- → 17β-HSD2 inhibitors for the treatment of osteoporosis: Identification of a promising scaffold(2010)43 cited
- → Discovery of a new class of bicyclic substituted hydroxyphenylmethanones as 17β-hydroxysteroid dehydrogenase type 2 (17β-HSD2) inhibitors for the treatment of osteoporosis(2011)25 cited
- → Structural Optimization of 2,5-Thiophene Amides as Highly Potent and Selective 17β-Hydroxysteroid Dehydrogenase Type 2 Inhibitors for the Treatment of Osteoporosis(2012)24 cited
- → Triazole ring-opening leads to the discovery of potent nonsteroidal 17β-hydroxysteroid dehydrogenase type 2 inhibitors(2011)15 cited
- → Synthesis and Biological Evaluation of Spiro-δ-lactones as Inhibitors of 17β-Hydroxysteroid Dehydrogenase Type 2 (17β-HSD2)(2011)12 cited
- → Development of potent and selective inhibitors of 17β-hydroxysteroid dehydrogenase type 2 : a new target for the treatment of osteoporosis(2011)
- → ChemInform Abstract: Triazole Ring‐Opening Leads to the Discovery of Potent Nonsteroidal 17β‐Hydroxysteroid Dehydrogenase Type 2 Inhibitors.(2012)