Panagiota Roumelioti
University of Patras(GR)
Publications by Year
Research Areas
Chemical Synthesis and Analysis, Receptor Mechanisms and Signaling, Computational Drug Discovery Methods, Neuropeptides and Animal Physiology, Blood Coagulation and Thrombosis Mechanisms
Most-Cited Works
- → An Effort To Understand the Molecular Basis of Hypertension through the Study of Conformational Analysis of Losartan and Sarmesin Using a Combination of Nuclear Magnetic Resonance Spectroscopy and Theoretical Calculations(1999)121 cited
- → The design and synthesis of a potent angiotensin II cyclic analogue confirms the ring cluster receptor conformation of the hormone angiotensin II(2000)44 cited
- → Synthesis and study of a cyclic angiotensin II antagonist analogue reveals the role of π*–π* interactions in the C-terminal aromatic residue for agonist activity and its structure resemblance with AT1 non-peptide antagonists(2001)36 cited
- → Conformation and Bioactivity. Design and Discovery of Novel Antihypertensive Drugs(2004)33 cited
- → An efficient synthesis of a rationally designed 1,5 disubstituted imidazole AT1 Angiotensin II receptor antagonist: reorientation of imidazole pharmacophore groups in losartan reserves high receptor affinity and confirms docking studies(2010)21 cited
- → Design, synthesis and biological evaluation of cyclic angiotensin II analogues with 3,5 side-Chain bridges(2002)21 cited
- → Design and synthesis of small semi-mimetic peptides with immunomodulatory activity based on Myelin Basic Protein (MBP)(1998)15 cited
- → Conformational and biological studies for a pair of novel synthetic AT1 antagonists: stereoelectronic requirements for antihypertensive efficacy(2003)15 cited
- → Structural comparison between type I and type II antagonists: possible implications in the drug design of AT1 antagonists(2000)12 cited
- → Design and Synthesis of Novel Biologically Active Thrombin Receptor Non-Peptide Mimetics Based on the Pharmacophoric Cluster Phe/Arg/NH2of the Ser42-Phe-Leu-Leu-Arg46Motif Sequence: Platelet Aggregation and Relaxant Activities(2004)11 cited