John A. Tallarico
Novartis (Switzerland)(CH)Novartis (China)(CN)
Publications by Year
Research Areas
Protein Degradation and Inhibitors, Ubiquitin and proteasome pathways, Chemical Synthesis and Analysis, Synthetic Organic Chemistry Methods, Click Chemistry and Applications
Most-Cited Works
- → Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling(2009)2,067 cited
- → Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo(2014)724 cited
- → Disordered methionine metabolism in MTAP/CDKN2A-deleted cancers leads to dependence on PRMT5(2016)552 cited
- → SMN2 splice modulators enhance U1–pre-mRNA association and rescue SMA mice(2015)426 cited
- → Harnessing the anti-cancer natural product nimbolide for targeted protein degradation(2019)412 cited
- → Integrating high-content screening and ligand-target prediction to identify mechanism of action(2007)351 cited
- → Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications