Jason S. Ngui
Publications by Year
Research Areas
Pharmacogenetics and Drug Metabolism, Drug Transport and Resistance Mechanisms, Inflammatory mediators and NSAID effects, Carcinogens and Genotoxicity Assessment, Estrogen and related hormone effects
Most-Cited Works
- → Cytochrome P450 3A4-Mediated Bioactivation of Raloxifene: Irreversible Enzyme Inhibition and Thiol Adduct Formation(2002)156 cited
- → Enzyme Kinetics of Cytochrome P450-Mediated Reactions(2005)120 cited
- In vitro stimulation of warfarin metabolism by quinidine: increases in the formation of 4'- and 10-hydroxywarfarin.(2001)
- Bioactivation of diclofenac via benzoquinone imine intermediates-identification of urinary mercapturic acid derivatives in rats and humans.(2001)
- → Cytochrome P450 3A4-Mediated Interaction of Diclofenac and Quinidine(2000)73 cited
- → In Vitro Bioactivation of Dihydrobenzoxathiin Selective Estrogen Receptor Modulators by Cytochrome P450 3A4 in Human Liver Microsomes: Formation of Reactive Iminium and Quinone Type Metabolites(2005)59 cited
- → Induction of Hepatic CYP2B Is a More Sensitive Indicator of Exposure to Aroclor 1260 than CYP1A in Male Rats(1999)28 cited
- → Assessing and minimizing time-dependent inhibition of cytochrome P450 3A in drug discovery: A case study with melanocortin-4 receptor agonists(2008)18 cited
- → Influence of different recombinant systems on the cooperativity exhibited by cytochrome P4503A4(2004)17 cited
- → Metabolism of a Thiazole Benzenesulfonamide Derivative, a Potent and Selective Agonist of the Human β3-Adrenergic Receptor, in Rats: Identification of a Novel Isethionic Acid Conjugate(2002)13 cited