Celia R. Berkers
Utrecht University(NL)
Publications by Year
Research Areas
Ubiquitin and proteasome pathways, Protein Degradation and Inhibitors, Cancer, Hypoxia, and Metabolism, Multiple Myeloma Research and Treatments, HIV/AIDS drug development and treatment
Most-Cited Works
- → Serine starvation induces stress and p53-dependent metabolic remodelling in cancer cells(2012)1,026 cited
- → A novel orally active proteasome inhibitor induces apoptosis in multiple myeloma cells with mechanisms distinct from Bortezomib(2005)695 cited
- → Crystal Structure of the Boronic Acid-Based Proteasome Inhibitor Bortezomib in Complex with the Yeast 20S Proteasome(2006)469 cited
- → Molecular basis of bortezomib resistance: proteasome subunit β5 (PSMB5) gene mutation and overexpression of PSMB5 protein(2008)445 cited
- → Metabolic Regulation by p53 Family Members(2013)441 cited
- → Stabilization of the Transcription Factor Foxp3 by the Deubiquitinase USP7 Increases Treg-Cell-Suppressive Capacity(2013)303 cited
- → Activity probe for in vivo profiling of the specificity of proteasome inhibitor bortezomib(2005)265 cited
- → The Influence of Metabolism on Drug Response in Cancer(2018)264 cited
- → CEP-18770: A novel, orally active proteasome inhibitor with a tumor-selective pharmacologic profile competitive with bortezomib(2007)252 cited
- → Thermal profiling reveals phenylalanine hydroxylase as an off-target of panobinostat(2016)252 cited