Crystal MacKenzie
Publications by Year
Research Areas
Fibroblast Growth Factor Research, Estrogen and related hormone effects, Kruppel-like factors research, Click Chemistry and Applications, Cancer, Hypoxia, and Metabolism
Most-Cited Works
- → H3B-8800, an orally available small-molecule splicing modulator, induces lethality in spliceosome-mutant cancers(2018)500 cited
- → Cancer-Associated SF3B1 Hotspot Mutations Induce Cryptic 3′ Splice Site Selection through Use of a Different Branch Point(2015)458 cited
- → Circulating miRNA Biomarkers for Alzheimer's Disease(2013)376 cited
- → H3B-6527 Is a Potent and Selective Inhibitor of FGFR4 in FGF19-Driven Hepatocellular Carcinoma(2017)150 cited
- → Discovery of Selective Estrogen Receptor Covalent Antagonists for the Treatment of ERαWT and ERαMUT Breast Cancer(2018)109 cited
- → A phase I study of H3B-6527 in hepatocellular carcinoma (HCC) or intrahepatic cholangiocarcinoma (ICC) patients (pts).(2019)14 cited
- → Abstract DDT01-04: Discovery and development of H3B-6545: A novel, oral, selective estrogen receptor covalent antagonist (SERCA) for the treatment of breast cancer(2017)8 cited
- → Abstract P228: Preclinical pharmacokinetics and pharmacodynamics of KB-0742, a selective, oral CDK9 inhibitor(2021)7 cited
- → Abstract B159: A first-in-human study of CDK9 inhibitor KB-0742 demonstrates evidence of tolerability and clinical activity(2023)5 cited
- → P1–234: Circulating miRNA biomarkers for Alzheimer's disease(2013)2 cited