Sarah Mackenzie
Newcastle upon Tyne Hospitals NHS Foundation Trust(GB)
Publications by Year
Research Areas
Cell death mechanisms and regulation, Machine Learning in Bioinformatics, ATP Synthase and ATPases Research, Microbial Natural Products and Biosynthesis, Hippo pathway signaling and YAP/TAZ
Most-Cited Works
- → OTX015 (MK‐8628), a novel BET inhibitor, displays in vitro and in vivo antitumor effects alone and in combination with conventional therapies in glioblastoma models(2016)150 cited
- → Targeting Cell Death in Tumors by Activating Caspases(2008)105 cited
- → Epigenetic Control of Mitochondrial Fission Enables Self-Renewal of Stem-like Tumor Cells in Human Prostate Cancer(2019)100 cited
- The potential for caspases in drug discovery.(2010)
- → Death by Caspase Dimerization(2012)98 cited
- → Phase II Study of Oxaliplatin and Fluorouracil in Taxane- and Anthracycline-Pretreated Breast Cancer Patients(2002)56 cited
- → Tunable allosteric library of caspase-3 identifies coupling between conserved water molecules and conformational selection(2016)54 cited
- → Phase I Safety and Pharmacodynamic of Inecalcitol, a Novel VDR Agonist with Docetaxel in Metastatic Castration-Resistant Prostate Cancer Patients(2014)42 cited
- → Phase II study of oxaliplatin versus oxaliplatin combined with infusional 5-fluorouracil in hormone refractory metastatic prostate cancer patients(2003)38 cited
- → Modifying Caspase-3 Activity by Altering Allosteric Networks(2014)32 cited