Brian S. J. Blagg
University of Notre Dame(US)
Publications by Year
Research Areas
Heat shock proteins research, Computational Drug Discovery Methods, Protein Structure and Dynamics, ATP Synthase and ATPases Research, Enzyme Structure and Function
Most-Cited Works
- → A first-in-class polymerase theta inhibitor selectively targets homologous-recombination-deficient tumors(2021)326 cited
- → Novobiocin and Additional Inhibitors of the Hsp90 C-Terminal Nucleotide- binding Pocket(2008)307 cited
- → Novobiocin: Redesigning a DNA Gyrase Inhibitor for Selective Inhibition of Hsp90(2006)235 cited
- → Hsp90 inhibitors: Small molecules that transform the Hsp90 protein folding machinery into a catalyst for protein degradation(2005)199 cited
- → Swe1Wee1-Dependent Tyrosine Phosphorylation of Hsp90 Regulates Distinct Facets of Chaperone Function(2010)191 cited
- → Old and New Approaches to Target the Hsp90 Chaperone(2019)185 cited
- → Hsp90 Inhibitors Identified from a Library of Novobiocin Analogues(2005)171 cited
- → Gedunin, a Novel Hsp90 Inhibitor: Semisynthesis of Derivatives and Preliminary Structure−Activity Relationships(2008)163 cited
- → Engineering an Antibiotic to Fight Cancer: Optimization of the Novobiocin Scaffold to Produce Anti-proliferative Agents(2011)162 cited
- → The Design, Synthesis, and Evaluation of Coumarin Ring Derivatives of the Novobiocin Scaffold that Exhibit Antiproliferative Activity(2008)153 cited