Hasim Zecic
La Roche College(US)
Publications by Year
Research Areas
Synthesis and biological activity, Melanoma and MAPK Pathways, Synthesis of Tetrazole Derivatives, Catalytic C–H Functionalization Methods, Catalytic Alkyne Reactions
Most-Cited Works
- → Structure-Based Drug Design of RN486, a Potent and Selective Bruton’s Tyrosine Kinase (BTK) Inhibitor, for the Treatment of Rheumatoid Arthritis(2014)107 cited
- → Discovery of 6-(2,4-Difluorophenoxy)-2-[3-hydroxy-1-(2-hydroxyethyl)propylamino]-8-methyl-8H-pyrido[2,3-d]pyrimidin-7-one (Pamapimod) and 6-(2,4-Difluorophenoxy)-8-methyl-2-(tetrahydro-2H-pyran-4-ylamino)pyrido[2,3-d]pyrimidin-7(8H)-one (R1487) as Orally Bioavailable and Highly Selective Inhibitors of p38α Mitogen-Activated Protein Kinase(2011)74 cited
- → Platinum(II)-catalyzed intramolecular cyclization of alkynylbenzonitriles: synthesis of 1-alkoxyisoquinolines and isoquinolones(2010)29 cited
- → 3-Amino-pyrazolo[3,4-d]pyrimidines as p38α kinase inhibitors: Design and development to a highly selective lead(2011)27 cited
- → Synthesis of Heteroaryl-fused Pyrazoles as P38 Kinase Inhibitors(2009)8 cited
- → ChemInform Abstract: Synthesis of Heteroaryl‐Fused Pyrazoles as P38 Kinase Inhibitors.(2010)
- → ChemInform Abstract: Platinum(II)‐Catalyzed Intramolecular Cyclization of Alkynylbenzonitriles: Synthesis of 1‐Alkoxyisoquinolines and Isoquinolones.(2011)