Yury Kapelyukh
University of Dundee(GB)Ninewells Hospital(GB)
Publications by Year
Research Areas
Pharmacogenetics and Drug Metabolism, Computational Drug Discovery Methods, Receptor Mechanisms and Signaling, Drug Transport and Resistance Mechanisms, Hormonal Regulation and Hypertension
Most-Cited Works
- → Quantitative Prediction of Human Pregnane X Receptor and Cytochrome P450 3A4 Mediated Drug-Drug Interaction in a Novel Multiple Humanized Mouse Line(2011)85 cited
- → Defining the Contribution of CYP1A1 and CYP1A2 to Drug Metabolism Using Humanized CYP1A1/1A2 and Cyp1a1/Cyp1a2 Knockout Mice(2019)58 cited
- → Modeling Human Cytochrome P450 2D6 Metabolism and Drug-Drug Interaction by a Novel Panel of Knockout and Humanized Mouse Lines(2011)56 cited
- → Multiple Substrate Binding by Cytochrome P450 3A4: Estimation of the Number of Bound Substrate Molecules(2008)54 cited
- → Generation and Characterization of Novel Cytochrome P450 Cyp2c Gene Cluster Knockout and CYP2C9 Humanized Mouse Lines(2012)54 cited
- → In Vivo Responses of the Human and Murine Pregnane X Receptor to Dexamethasone in Mice(2010)46 cited
- → An Extensively Humanized Mouse Model to Predict Pathways of Drug Disposition and Drug/Drug Interactions, and to Facilitate Design of Clinical Trials(2019)39 cited
- → A Role for Cytochrome b5 in the In Vivo Disposition of Anticancer and Cytochrome P450 Probe Drugs in Mice(2013)31 cited
- → Defining Human Pathways of Drug Metabolism In Vivo through the Development of a Multiple Humanized Mouse Model(2015)23 cited
- → Quantifying ERK activity in response to inhibition of the BRAFV600E-MEK-ERK cascade using mathematical modelling(2021)13 cited