Sophie Le Pogam
Publications by Year
Research Areas
Hepatitis C virus research, Hepatitis B Virus Studies, HIV/AIDS drug development and treatment, Biochemical and Molecular Research, Liver Disease Diagnosis and Treatment
Most-Cited Works
- → The Novel Nucleoside Analog R1479 (4′-Azidocytidine) Is a Potent Inhibitor of NS5B-dependent RNA Synthesis and Hepatitis C Virus Replication in Cell Culture(2005)215 cited
- → The Hepatitis C Virus Replicon Presents a Higher Barrier to Resistance to Nucleoside Analogs than to Nonnucleoside Polymerase or Protease Inhibitors(2008)164 cited
- → Existence of hepatitis C virus NS5B variants naturally resistant to non-nucleoside, but not to nucleoside, polymerase inhibitors among untreated patients(2008)134 cited
- → Selection and Characterization of Replicon Variants Dually Resistant to Thumb- and Palm-Binding Nonnucleoside Polymerase Inhibitors of the Hepatitis C Virus(2006)131 cited
- → In vitro selected Con1 subgenomic replicons resistant to 2′-C-Methyl-Cytidine or to R1479 show lack of cross resistance(2006)128 cited
- → In Vivo Emergence of a Novel Mutant L159F/L320F in the NS5B Polymerase Confers Low-Level Resistance to the HCV Polymerase Inhibitors Mericitabine and Sofosbuvir(2013)116 cited
- → Cloning, expression, and nucleotide sequence of genes involved in production of lactococcin DR, a bacteriocin from lactococcus lactis subsp. lactis(1994)109 cited
- → Selected Replicon Variants with Low-Level In Vitro Resistance to the Hepatitis C Virus NS5B Polymerase Inhibitor PSI-6130 Lack Cross-Resistance with R1479(2008)106 cited
- → Design, synthesis, and antiviral properties of 4′-substituted ribonucleosides as inhibitors of hepatitis C virus replication: The discovery of R1479(2007)96 cited
- → Hepatitis C in a Hemodialysis Unit: Molecular Evidence for Nosocomial Transmission(1998)95 cited