Kelvin Sham
Wellcome/MRC Cambridge Stem Cell Institute(GB)University of Cambridge(GB)
Publications by Year
Research Areas
Sphingolipid Metabolism and Signaling, Advanced biosensing and bioanalysis techniques, Synthesis and biological activity, Ion channel regulation and function, RNA Interference and Gene Delivery
Most-Cited Works
- → Synthesis of Aromatic Heterocycles via Palladium-Catalyzed Annulation of Internal Alkynes(1995)289 cited
- → First X-ray Cocrystal Structure of a Bacterial FabH Condensing Enzyme and a Small Molecule Inhibitor Achieved Using Rational Design and Homology Modeling(2002)72 cited
- → Discovery of Highly Selective and Potent p38 Inhibitors Based on a Phthalazine Scaffold(2008)58 cited
- → Pharmacological characterization of potent and selective NaV1.7 inhibitors engineered from Chilobrachys jingzhao tarantula venom peptide JzTx-V(2018)49 cited
- → Discovery of Tarantula Venom-Derived NaV1.7-Inhibitory JzTx-V Peptide 5-Br-Trp24 Analogue AM-6120 with Systemic Block of Histamine-Induced Pruritis(2018)32 cited
- → 3-Amino-7-phthalazinylbenzoisoxazoles as a Novel Class of Potent, Selective, and Orally Available Inhibitors of p38α Mitogen-Activated Protein Kinase(2008)26 cited
- → Plasma and Liver Protein Binding of N-Acetylgalactosamine–Conjugated Small Interfering RNA(2019)25 cited
- → Identification and Optimization of a Minor Allele-Specific siRNA to Prevent PNPLA3 I148M-Driven Nonalcoholic Fatty Liver Disease(2021)22 cited
- → The optimization of aminooxadiazoles as orally active inhibitors of Cdc7(2013)21 cited
- → (E)-3-[6-[[(2,6-Dichlorophenyl)thio]methyl]-3-(2-phenylethoxy)-2-pyridinyl]-2- propenoic Acid: A High-Affinity Leukotriene B4 Receptor Antagonist with Oral Antiinflammatory Activity(1996)21 cited