Wen‐Cherng Lee
Biogen (United States)(US)
Publications by Year
Research Areas
TGF-β signaling in diseases, Cell Adhesion Molecules Research, Protein Kinase Regulation and GTPase Signaling, Chemical Synthesis and Analysis, Carbohydrate Chemistry and Synthesis
Most-Cited Works
- → Heat Shock Protein 90: Inhibitors in Clinical Trials(2009)282 cited
- → Selective, Tight-Binding Inhibitors of Integrin α4β1 That Inhibit Allergic Airway Responses(1999)207 cited
- → Successful shape-Based virtual screening: The discovery of a potent inhibitor of the type I TGFβ receptor kinase (TβRI)(2003)166 cited
- → A Novel Small-Molecule Inhibitor of Transforming Growth Factor β Type I Receptor Kinase (SM16) Inhibits Murine Mesothelioma Tumor Growth In vivo and Prevents Tumor Recurrence after Surgical Resection(2007)113 cited
- → Discovery of a potent and highly selective PDK1 inhibitor via fragment-based drug discovery(2011)85 cited
- → SM16, an Orally Active TGF-β Type I Receptor Inhibitor Prevents Myofibroblast Induction and Vascular Fibrosis in the Rat Carotid Injury Model(2008)84 cited
- → The small molecule TGF-β signaling inhibitor SM16 synergizes with agonistic OX40 antibody to suppress established mammary tumors and reduce spontaneous metastasis(2011)66 cited
- → Identification of Potent and Novel α4β1 Antagonists Using in Silico Screening(2002)57 cited
- → Strategies for TGF-β modulation: a review of recent patents(2009)50 cited
- → TGF-Beta Type I Receptor (Alk5) Kinase Inhibitors in Oncology(2011)37 cited