Irina Kazakevich
Pharmaceutical Formulations (United States)(US)
Publications by Year
Research Areas
Diet, Metabolism, and Disease, Enzyme Structure and Function, Alzheimer's disease research and treatments, Biofuel production and bioconversion, Computational Drug Discovery Methods
Most-Cited Works
- → Discovery of the 3-Imino-1,2,4-thiadiazinane 1,1-Dioxide Derivative Verubecestat (MK-8931)–A β-Site Amyloid Precursor Protein Cleaving Enzyme 1 Inhibitor for the Treatment of Alzheimer’s Disease(2016)161 cited
- → Design and Validation of Bicyclic Iminopyrimidinones As Beta Amyloid Cleaving Enzyme-1 (BACE1) Inhibitors: Conformational Constraint to Favor a Bioactive Conformation(2012)56 cited
- → Cyclic Hydroxyamidines as Amide Isosteres: Discovery of Oxadiazolines and Oxadiazines as Potent and Highly Efficacious γ-Secretase Modulators in Vivo(2011)52 cited
- → Structure-Based Design of an Iminoheterocyclic β-Site Amyloid Precursor Protein Cleaving Enzyme (BACE) Inhibitor that Lowers Central Aβ in Nonhuman Primates(2016)42 cited
- → USP Apparatus 4: a Valuable In Vitro Tool to Enable Formulation Development of Long-Acting Parenteral (LAP) Nanosuspension Formulations of Poorly Water-Soluble Compounds(2017)28 cited
- → Amorphization of itraconazole by inorganic pharmaceutical excipients: comparison of excipients and processing methods(2014)17 cited
- → Screening of glucose isomerase-producing microorganisms(1997)12 cited
- → A Plate Method to Screen for Microorganisms Producing Xylose Isomerase(2004)6 cited
- → Biosynthetic features and properties of xylose isomerases from Arthrobacter nicotianae, Escherichia coli, and Erwinia carotovora subsp. atroseptica(2006)3 cited
- → Investigation of the synthesis of xylose/glucose isomerases in sixArthrobacter sp. strains(2000)2 cited