a public good project by the
Synthesis
Company
of California

© 2026

Harumi Takahashi | doi.page

0 works0 citations0 h-index

Harumi Takahashi

Publications by Year

Research Areas

Pharmacogenetics and Drug Metabolism, Pancreatic function and diabetes, Hormonal Regulation and Hypertension, Eicosanoids and Hypertension Pharmacology, Diabetes Treatment and Management

Most-Cited Works

→ Essential role of Epac2/Rap1 signaling in regulation of insulin granule dynamics by cAMP(2007)418 cited
→ Different contributions of polymorphisms in VKORC1 and CYP2C9 to intra- and inter-population differences in maintenance dose of warfarin in Japanese, Caucasians and African-Americans(2006)374 cited
→ Pharmacogenetics of Warfarin Elimination and its Clinical Implications(2001)313 cited
→ Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study(2013)274 cited
→ The cAMP Sensor Epac2 Is a Direct Target of Antidiabetic Sulfonylurea Drugs(2009)219 cited
→ Population differences in S‐warfarin metabolism between CYP2C9 genotype‐matched Caucasian and Japanese patients(2003)189 cited

→ Metabolism of warfarin enantiomers in Japanese patients with heart disease having different CYP2C9 and CYP2C19 genotypes*(1998)

184 cited

→ Comparisons between in-vitro and in-vivo metabolism of (S)-warfarin: catalytic activities of cDNA-expressed CYP2C9, its Leu359 variant and their mixture versus unbound clearance in patients with the corresponding CYP2C9 genotypes(1998)163 cited

→ Glutamate Acts as a Key Signal Linking Glucose Metabolism to Incretin/cAMP Action to Amplify Insulin Secretion(2014)154 cited

→ Roles of cAMP signalling in insulin granule exocytosis(2009)117 cited