Ulrich Grädler
Merck (Germany)(DE)Merz (Germany)(DE)
Publications by Year
Research Areas
Liver physiology and pathology, Gastrointestinal Tumor Research and Treatment, Mast cells and histamine, Platelet Disorders and Treatments, Computational Drug Discovery Methods
Most-Cited Works
- → Large-Scale Assessment of Binding Free Energy Calculations in Active Drug Discovery Projects(2020)296 cited
- → Estimation of Drug-Target Residence Times by τ-Random Acceleration Molecular Dynamics Simulations(2018)257 cited
- → EMD 1214063 and EMD 1204831 Constitute a New Class of Potent and Highly Selective c-Met Inhibitors(2013)143 cited
- → Virtual Screening for Submicromolar Leads of tRNA-guanine Transglycosylase Based on a New Unexpected Binding Mode Detected by Crystal Structure Analysis(2003)103 cited
- → Structural and Biophysical Characterization of the Syk Activation Switch(2012)88 cited
- → Identification and optimization of pyridazinones as potent and selective c-Met kinase inhibitors(2015)88 cited
- → A new target for shigellosis: rational design and crystallographic studies of inhibitors of tRNA-guanine transglycosylase11Edited by R. Huber(2001)76 cited
- → Fragment-Based Discovery of New Highly Substituted 1H-Pyrrolo[2,3-b]- and 3H-Imidazolo[4,5-b]-Pyridines as Focal Adhesion Kinase Inhibitors(2013)70 cited
- → Molecular basis of human ATM kinase inhibition(2021)59 cited
- → Ligand Desolvation Steers On-Rate and Impacts Drug Residence Time of Heat Shock Protein 90 (Hsp90) Inhibitors(2018)53 cited