Manfred Koegl
Boehringer Ingelheim (Austria)(AT)
Publications by Year
Research Areas
Ubiquitin and proteasome pathways, Protein Degradation and Inhibitors, Peptidase Inhibition and Analysis, Chromatin Remodeling and Cancer, Monoclonal and Polyclonal Antibodies Research
Most-Cited Works
- → A Novel Ubiquitination Factor, E4, Is Involved in Multiubiquitin Chain Assembly(1999)1,051 cited
- → BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design(2019)560 cited
- → Drugging an undruggable pocket on KRAS(2019)420 cited
- → Iterative Design and Optimization of Initially Inactive Proteolysis Targeting Chimeras (PROTACs) Identify VZ185 as a Potent, Fast, and Selective von Hippel–Lindau (VHL) Based Dual Degrader Probe of BRD9 and BRD7(2018)326 cited
- → Csk inhibition of c-Src activity requires both the SH2 and SH3 domains of Src.(1993)274 cited
- → The phosphatidylinositol 3-kinase alpha is required for DNA synthesis induced by some, but not all, growth factors.(1994)265 cited