Venkatraman Junnotula

Publications by Year

Research Areas

Synthesis and Biological Evaluation, Glycosylation and Glycoproteins Research, Cancer, Hypoxia, and Metabolism, Analytical Chemistry and Chromatography, Crystallization and Solubility Studies

Most-Cited Works

• → Initiation of DNA Strand Cleavage by 1,2,4-Benzotriazine 1,4-Dioxide Antitumor Agents: Mechanistic Insight from Studies of 3-Methyl-1,2,4-benzotriazine 1,4-Dioxide(2008)60 cited
• → Synthesis and Biological Evaluation of New 2-Arylcarbonyl-3-trifluoromethylquinoxaline 1,4-Di-N-oxide Derivatives and Their Reduced Analogues(2007)57 cited
• → DNA Strand Damage Product Analysis Provides Evidence That the Tumor Cell-Specific Cytotoxin Tirapazamine Produces Hydroxyl Radical and Acts as a Surrogate for O₂(2007)55 cited
• → DNA strand cleaving properties and hypoxia-selective cytotoxicity of 7-chloro-2-thienylcarbonyl-3-trifluoromethylquinoxaline 1,4-dioxide(2010)26 cited
• → Development and validation of a simple and sensitive method for quantification of levodopa and carbidopa in rat and monkey plasma using derivatization and UPLC–MS/MS(2013)25 cited
• → Isotopic Labeling Experiments That Elucidate the Mechanism of DNA Strand Cleavage by the Hypoxia-Selective Antitumor Agent 1,2,4-Benzotriazine 1,4-Di-N-oxide(2013)16 cited
• → Development of a multi-sugar LC-MS/MS assay using simple chemical derivatization with acetic anhydride(2016)9 cited
• → LC-MS/MS quantification of dimethyl fumarate and methyl hydrogen fumarate in rat blood using tiopronin as trapping reagent(2016)9 cited
• → Development of an ultra-sensitive assay for the determination of an aminoalkyl glucosaminide 4-phosphate, GSK1795091, in plasma to support a first time in human study(2018)6 cited
• → Analytical approaches for quantification of a Nrf2 pathway activator: overcoming bioanalytical challenges to support a toxicity study(2014)6 cited